GTX00972
TRAF4 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00972
- Zusätzliche Namen:
- CART1 , MLN62 , RNF83 , TNF receptor associated factor 4 , TRAF4
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 5mg BSA, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg Thimerosal, 0.05mg Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human TRAF4(437-454aa PKFISHQDIRKRNYVRDD), identical to the related rat and mouse sequences.
- Uniprot:
- Q9BUZ4
- Synonyme:
- CART1;cysteine-rich domain associated with ring and TRAF domain;cysteine-rich domain associated with RING and Traf domains protein 1;malignant 62;metastatic lymph node gene 62 protein;MLN 62;MLN62;RING finger protein 83;RNF83;TNF receptor-associated factor 4;TRAF4 variant 6;tumor necrosis receptor-associated factor 4A
- Weitere Details:
- This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice