GTX00886
RAD18 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00886
- Zusätzliche Namen:
- RAD18 E3 ubiquitin protein ligase , RAD18 , RAD18, E3 ubiquitin protein ligase , RNF73
- Anwendung:
- WB, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, no preservatives.
- Immunogen:
- GST-fusion protein containing 113 carboxyl terminal of human Rad18
- Uniprot:
- Q9NS91
- Synonyme:
- E3 ubiquitin-protein ligase RAD18;hHR18;hRAD18;postreplication repair protein hRAD18p;postreplication repair protein RAD18;RAD18 homolog;RAD18, S. cerevisiae, homolog;RING finger protein 73;RING-type E3 ubiquitin transferase RAD18;RNF73
- Weitere Details:
- The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice