Prion Protein (PrP) antibody [7A1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX00857
Zusätzliche Namen:: prion protein , ASCR , AltPrP , CD230 , CJD , GSS , KURU , PRIP , PRNP , PrP , PrP2730 , PrP3335C , PrPc , p2730 , Prion protein PrP
Anwendung:: ELISA, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Filter-sterilized PBS, 50% Glycerol, no preservatives.
Immunogen:: Recombinant human PrP lacking GPI anchor expressed and purified from rabbit kidney cell line RK13
Klon:: 7A1
Uniprot:: P04156
Synonyme:: alternative prion protein;AltPrP;ASCR;CD230;CD230 antigen;CJD;GSS;KURU;major prion protein;p27-30;prion-related protein;PRIP;PrP;PrP27-30;PrP33-35C;PrPc
Weitere Details:: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Versandbedingungen:: Blue Ice