LILRB1 antibody [GHI/75]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX00517
Zusätzliche Namen:: CD85J , ILT2 , LILRB1 , LIR1 , MIR7 , PIRB , leukocyte immunoglobulin like receptor B1
Anwendung:: Flow Cytometry, WB, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Hairy cell leukaemia cells
Klon:: GHI/75
Uniprot:: Q8NHL6
Synonyme:: CD85 antigen-like family member J;CD85J;Ig-like transcript 2;ILT-2;ILT2;immunoglobulin heavy chain variable region;Immunoglobulin-like transcript 2;leucocyte Ig-like receptor B1;leukocyte immunoglobulin-like receptor subfamily B member 1;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1;LIR-1;LIR1;MIR-7;MIR7;monocyte/macrophage immunoglobulin-like receptor 7;myeloid inhibitory receptor 7;PIR-B;PIRB
Weitere Details:: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice