![uPAR antibody [VIM5]](https://www.genetex.com/upload/website/prouct_img/normal/GTX00512/GTX00512_20191025_AP_006_49_w_23053121_721.webp)
GTX00512
uPAR antibody [VIM5]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00512
- Zusätzliche Namen:
- CD87 , PLAUR , UPAR , URKR , plasminogen activator, urokinase receptor , uPA Receptor , uPAR
- Anwendung:
- Flow Cytometry
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- human myeloid cell line THP-1
- Klon:
- VIM5
- Uniprot:
- Q03405
- Synonyme:
- CD87;monocyte activation antigen Mo3;U-PAR;u-plasminogen activator receptor form 2;UPAR;URKR;urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
- Weitere Details:
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice