![CD160 antibody [BY55]](https://www.genetex.com/upload/website/prouct_img/normal/GTX00488/GTX00488_20191025_AP_006_29_w_23053121_268.webp)
GTX00488
CD160 antibody [BY55]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00488
- Zusätzliche Namen:
- BY55 , CD160 , CD160 molecule , NK1 , NK28
- Anwendung:
- Flow Cytometry, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- TBS, 15mM Sodium azide.
- Immunogen:
- Human NK cell line YT2C2
- Klon:
- BY55
- Uniprot:
- O95971
- Synonyme:
- BY55;CD160 antigen;CD160-delta Ig;natural killer cell receptor BY55;natural killer cell receptor, immunoglobulin superfamily member;NK1;NK28
- Weitere Details:
- CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice