GTX00481
CD11b antibody [ICRF44]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00481
- Zusätzliche Namen:
- integrin subunit alpha M , CD11B , CR3A , MAC-1 , MAC1A , MO1A , SLEB6
- Anwendung:
- Flow Cytometry, WB, IHC-Fr, IF, ICC, IP, Neutralisation
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human, Porcine
- Buffer:
- 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
- Immunogen:
- Rheumatoid synovial cells and human monocytes.
- Klon:
- ICRF44
- Uniprot:
- P11215
- Synonyme:
- antigen CD11b (p170);CD11 antigen-like family member B;CD11B;cell surface glycoprotein MAC-1 subunit alpha;complement component 3 receptor 3 subunit;CR-3 alpha chain;CR3A;integrin alpha-M;integrin, alpha M (complement component 3 receptor 3 subunit);leukocyte adhesion receptor MO1;MAC-1;MAC1A;macrophage antigen alpha polypeptide;macrophage-1 antigen alpha subunit;MO1A;Neutrophil adherence receptor;neutrophil adherence receptor alpha-M subunit;SLEB6
- Weitere Details:
- This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Versandbedingungen:
- Blue Ice