GTX00191-PRO
Human MMP13 protein, His tag (active)
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX00191-PRO
- Zusätzliche Namen:
- matrix metallopeptidase 13 , CLG3 , MANDP1 , MDST , MMP-13
- Anwendung:
- FuncS
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
- Immunogen:
- matrix metallopeptidase 13
- Spezies:
- Human
- Uniprot:
- P45452
- Synonyme:
- CLG3;collagenase 3;MANDP1;matrix metalloproteinase 13 (collagenase 3);Matrix metalloproteinase-13;MDST;MMP-13
- Weitere Details:
- This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
- Versandbedingungen:
- Blue Ice