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  2. Recombinant Proteins

GTX00093-PRO

Human IL4 protein, His tag (active)

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX00093-PRO
Zusätzliche Namen:
interleukin 4 , BCGF-1 , BCGF1 , BSF-1 , BSF1 , IL-4
Anwendung:
FuncS
Physischer Zustand:
Lyophilized
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Buffer:
Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Immunogen:
interleukin 4
Spezies:
Human
Uniprot:
P05112
Synonyme:
B cell growth factor 1;B_cell stimulatory factor 1;B-cell stimulatory factor 1;BCGF-1;BCGF1;binetrakin;BSF-1;BSF1;IL-4;interleukin 4 variant 2;interleukin-4;lymphocyte stimulatory factor 1;pitrakinra
Weitere Details:
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice