Human TNF beta Protein

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£497.00

SKU:: PME30085
Zusätzliche Namen:: Lymphotoxin-Alpha;LT-Alpha;TNF-Beta;Tumor Necrosis Factor Ligand Superfamily Member 1;LTA;TNFB;TNFSF1
Molekulargewicht:: 18.8 KDa
Reinheit:: Greater than 95% as determined by reducing SDS-PAGE.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
Target:: TNF
Not available:: Not available
Weitere Details:: Tumor Necrosis Factor β (TNF-β) is a secreted protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/TNFR1; TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form; binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-β forms heterotrimers with lymphotoxin-beta; which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory; immunostimulatory; and antiviral response; involves in the formation of second lymphoid organs during development; has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.