Human CCL8 (C-6His) Protein

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£423.00

SKU:: PME30056
Zusätzliche Namen:: C-C Motif Chemokine 8;HC14;Monocyte Chemoattractant Protein 2;Monocyte Chemotactic Protein 2;MCP-2;Small-Inducible Cytokine A8;CCL8;MCP2;SCYA10;SCYA8
Molekulargewicht:: 9.95 KDa
Reinheit:: Greater than 95% as determined by reducing SDS-PAGE.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; 1mM EDTA; pH 7.4.
Target:: CCL8
Not available:: Not available
Weitere Details:: Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3; respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells; including mast cells; eosinophils and basophils; which are implicated in allergic response; and monocytes; T cells; and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1; CCR2B and CCR5.