PME30026
Human Vitronectin (N-Truncated; C-6His) Protein
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£202.00
- SKU:
- PME30026
- Zusätzliche Namen:
- Complement S-protein;epibolin;Serum Spreading Factor;Serum-spreading factor;Somatomedin B;S-protein;V75;Vitronectin;VN;VNT;VTN
- Molekulargewicht:
- 48.3 KDa
- Reinheit:
- Greater than 90% as determined by reducing SDS-PAGE.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
- Target:
- Vitronectin
- Not available:
- Not available
- Weitere Details:
- Vitronectin; also known as VTN; is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process; including blood coagulation; fibrinolysis; pericellular proteolysis; complement dependent immune responses; and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H; respectively. In addition; Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
- Versandbedingungen:
- Ambient