Human PDGF-BB Protein

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£599.00

SKU:: PME30015
Zusätzliche Namen:: PDGFBB;PDGF-BB
Molekulargewicht:: 12.42 KDa
Reinheit:: Greater than 98% as determined by reducing SDS-PAGE.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc; pH 4.5.
Target:: PDGF-BB
Not available:: Not available
Weitere Details:: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB); where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition; PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.