Human G-CSF Protein

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£599.00

SKU:: PME30003
Zusätzliche Namen:: Granulocyte Colony-Stimulating Factor;G-CSF;Pluripoietin;Filgrastim;Lenograstim;CSF3;C17orf33;GCSF
Molekulargewicht:: 18.8 KDa
Reinheit:: Greater than 95% as determined by reducing SDS-PAGE.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc; 150mM NaCl; 0.004% Tween 80; 5% Mannitol; pH 4.0.
Target:: G-CSF
Not available:: Not available
Weitere Details:: Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival; proliferation; and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors; G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins; TNF; Interleukin-1; and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial; endothelial; and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.