Human CHRM3 Protein; hFc Tag

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£189.00

SKU:: PME101905
Zusätzliche Namen:: M3R; mAChR M3; ACHE2; MR3; hM3; MUSCARINIC M3 RECEPTOR
Molekulargewicht:: The protein has a predicted molecular mass of 33.2 kDa after removal of the signal peptide.
Reinheit:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CHRM3
CHRM3(Met1-Gln67) hFc(Glu99-Ala330):: CHRM3(Met1-Gln67) hFc(Glu99-Ala330)
Weitere Details:: CHRM3 encodes the muscarinic acetylcholine receptor M3; a G-protein coupled receptor (GPCR) that primarily couples to Gq/11 proteins; activating phospholipase C (PLC); increasing inositol triphosphate (IP₃) and diacylglycerol (DAG) levels; and mobilizing intracellular Ca²⁺. CHRM3 is widely expressed in smooth muscle; exocrine glands; pancreas; and the central nervous system; mediating smooth muscle contraction; glandular secretion; insulin release; and neuronal signaling.