PME101863
Human EPO Protein; hFc Tag
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£189.00
- SKU:
- PME101863
- Zusätzliche Namen:
- EP; DBAL; ECYT5; MVCD2
- Molekulargewicht:
- The protein has a predicted molecular mass of 44.5 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- EPO
- EPO(Ala28-Arg193) hFc(Glu99-Ala330):
- EPO(Ala28-Arg193) hFc(Glu99-Ala330)
- Weitere Details:
- This gene encodes a secreted; glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney; secreted into the blood plasma; and binds to the erythropoietin receptor to promote red blood cell production; or erythropoiesis; in the bone marrow. Expression of this gene is upregulated under hypoxic conditions; in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye; and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries; as well as antiapoptotic functions in several tissue types; and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq; Aug 2017]
- Versandbedingungen:
- Ambient