PME101832
Human OPN4 Protein; hFc Tag
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£194.00
- SKU:
- PME101832
- Zusätzliche Namen:
- MOP
- Molekulargewicht:
- The protein has a predicted molecular mass of 33.7 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- OPN4
- OPN4(Met1-Thr72) hFc(Glu99-Ala330):
- OPN4(Met1-Thr72) hFc(Glu99-Ala330)
- Weitere Details:
- Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse; retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse; this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates; but does not abolish; photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Jul 2008]
- Versandbedingungen:
- Ambient