PME101749
Human F7 Protein; Flag Tag
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£199.00
- SKU:
- PME101749
- Zusätzliche Namen:
- SPCA
- Molekulargewicht:
- The protein has a predicted molecular mass of 54.5 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- F7
- F7(Met1-Pro466) 3×Flag tag:
- F7(Met1-Pro466) 3×Flag tag
- Weitere Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form; and is converted to an active form by either factor IXa; factor Xa; factor XIIa; or thrombin by minor proteolysis. Upon activation of the factor VII; a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated; and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions; the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq; Aug 2015]
- Versandbedingungen:
- Ambient