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PME101655

Human GDF2 Protein; Flag Tag

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£199.00

SKU:
PME101655
Zusätzliche Namen:
BMP9; HHT5; BMP-9
Molekulargewicht:
The protein has a predicted molecular mass of 50.3 kDa after removal of the signal peptide.
Reinheit:
The purity of the protein is greater than 80% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
GDF2
GDF2(Met1-Arg429) 3×Flag tag:
GDF2(Met1-Arg429) 3×Flag tag
Weitere Details:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development; angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq; Jul 2016]
Versandbedingungen:
Ambient