PME101581
Human ROR1(30-164) Protein; hFc Tag
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£224.00
- SKU:
- PME101581
- Zusätzliche Namen:
- NTRKR1; dJ537F10.1
- Molekulargewicht:
- The protein has a predicted molecular mass of 41.1 kDa after removal of the signal peptide. The apparent molecular mass of ROR1(30-164)-hFc is approximately 35-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- ROR1
- ROR1(Gln30-Tyr164) hFc(Glu99-Ala330):
- ROR1(Gln30-Tyr164) hFc(Glu99-Ala330)
- Weitere Details:
- This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Jun 2012]
- Versandbedingungen:
- Ambient