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PME101535

Human CD3E Protein; His Tag

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£174.00

SKU:
PME101535
Zusätzliche Namen:
T3E; TCRE; IMD18; CD3epsilon
Molekulargewicht:
The protein has a predicted molecular mass of 13.1 kDa after removal of the signal peptide.
Reinheit:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CD3E
CD3E(Asp23-Asp126) 10×His tag:
CD3E(Asp23-Asp126) 10×His tag
Weitere Details:
The protein encoded by this gene is the CD3-epsilon polypeptide; which together with CD3-gamma; -delta and -zeta; and the T-cell receptor alpha/beta and gamma/delta heterodimers; forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon; gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq; Jul 2008]
Versandbedingungen:
Ambient