PME101442
Human TIM3 Protein; hFc Tag
Größe
£217.00
- SKU:
- PME101442
- Zusätzliche Namen:
- HAVCR2; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2
- Molekulargewicht:
- The protein has a predicted molecular mass of 46.1 kDa after removal of the signal peptide. The apparent molecular mass of TIM3-hFc is approximately 55-100 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TIM3
- TIM3(Ser22-Gly202) hFc(Glu99-Ala330):
- TIM3(Ser22-Gly202) hFc(Glu99-Ala330)
- Weitere Details:
- The protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance. [provided by RefSeq; Sep 2011]
- Versandbedingungen:
- Ambient