PME101314
Human CFD Protein; hFc Tag
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£169.00
- SKU:
- PME101314
- Zusätzliche Namen:
- ADIPSIN;ADN;DF;PFD
- Molekulargewicht:
- The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is approximately 55-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CFD
- CFD(Ile26-Ala253) hFc(Glu99-Ala330):
- CFD(Ile26-Ala253) hFc(Glu99-Ala330)
- Weitere Details:
- This gene encodes a member of the S1; or chymotrypsin; family of serine peptidases. This protease catalyzes the cleavage of factor B; the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine; a cell signaling protein secreted by adipocytes; which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency; which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq; Nov 2015]
- Versandbedingungen:
- Ambient