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PME101282

Human CHRM2 Protein; hFc Tag

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£169.00

SKU:
PME101282
Zusätzliche Namen:
HM2
Molekulargewicht:
The protein has a predicted molecular mass of 28.6 kDa after removal of the signal peptide. The apparent molecular mass of CHRM2-hFc is approximately 35-55 kDa due to glycosylation.
Reinheit:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CHRM2
CHRM2(Met1-Glu22) hFc(Glu99-Ala330):
CHRM2(Met1-Glu22) hFc(Glu99-Ala330)
Weitere Details:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition; phosphoinositide degeneration; and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq; Jul 2008]
Versandbedingungen:
Ambient