PME101253
Human KREMEN2 Protein; His Tag
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£178.00
- SKU:
- PME101253
- Zusätzliche Namen:
- KRM2
- Molekulargewicht:
- The protein has a predicted molecular mass of 36.8 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- KREMEN2
- KREMEN2(Gly26-Ala364) 6×His tag:
- KREMEN2(Gly26-Ala364) 6×His tag
- Weitere Details:
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6); and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle; WSC; and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq; Dec 2011]
- Versandbedingungen:
- Ambient