PME101192
Human TIMP1 Protein; hFc Tag
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£169.00
- SKU:
- PME101192
- Zusätzliche Namen:
- CLGI;EPA;EPO;HCI;TIMP;TIMP-1
- Molekulargewicht:
- The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of TIMP1-hFc is approximately 55-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TIMP1
- TIMP1(Cys24-Ala207) hFc(Glu99-Ala330):
- TIMP1(Cys24-Ala207) hFc(Glu99-Ala330)
- Weitere Details:
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs); a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs; the encoded protein is able to promote cell proliferation in a wide range of cell types; and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition; the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq; Jul 2008]
- Versandbedingungen:
- Ambient