PME101016
Human TGFB3 Protein; hFc Tag
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£171.00
- SKU:
- PME101016
- Zusätzliche Namen:
- ARVD; LDS5; RNHF; ARVD1; TGF-beta3
- Molekulargewicht:
- The protein has a predicted molecular mass of 58.2 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TGFB3
- TGFB3(Leu24-Arg300) hFc(Glu99-Ala330):
- TGFB3(Leu24-Arg300) hFc(Glu99-Ala330)
- Weitere Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide; and is found in either a latent form composed of a mature peptide homodimer; a LAP homodimer; and a latent TGF-beta binding protein; or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation; and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections; as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq; Aug 2016]
- Versandbedingungen:
- Ambient