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PME100915

Human BRD4 Protein; hFc Tag

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£177.00

SKU:
PME100915
Zusätzliche Namen:
CAP;HUNK1;HUNKI;MCAP
Molekulargewicht:
The protein has a predicted molecular mass of 178.4 kDa after removal of the signal peptide.
Reinheit:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
BRD4
BRD4(Met1-Phe1362) hFc(Glu99-Ala330):
BRD4(Met1-Phe1362) hFc(Glu99-Ala330)
Weitere Details:
The protein encoded by this gene is homologous to the murine protein MCAP; which associates with chromosomes during mitosis; and to the human RING3 protein; a serine/threonine kinase. Each of these proteins contains two bromodomains; a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1); which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq; Jul 2008]
Versandbedingungen:
Ambient