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PME100862

Human CLDN3 Protein; hFc Tag

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£219.00

SKU:
PME100862
Zusätzliche Namen:
C7orf1;CPE-R2;CPETR2;HRVP1;RVP1
Molekulargewicht:
The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3-hFc is approximately 35-40 kDa due to glycosylation.
Reinheit:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CLDN3
CLDN3(Arg30-Arg80) hFc(Glu99-Ala330):
CLDN3(Arg30-Arg80) hFc(Glu99-Ala330)
Weitere Details:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet; with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene; a member of the claudin family; is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin; and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq; Jul 2008]
Versandbedingungen:
Ambient