PME100830
Human C5AR1 Protein; hFc Tag
Größe
£202.00
- SKU:
- PME100830
- Zusätzliche Namen:
- C5A;C5AR;C5R1;CD88
- Molekulargewicht:
- The protein has a predicted molecular mass of 30.4 kDa after removal of the signal peptide.The apparent molecular mass of C5AR1-hFc is approximately 40-53 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- C5AR1
- C5AR1(Met1-Asp37) hFc(Glu99-Ala330):
- C5AR1(Met1-Asp37) hFc(Glu99-Ala330)
- Weitere Details:
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994; PubMed:8182049; PubMed:7622471; PubMed:9553099; PubMed:10636859; PubMed:15153520; PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus; and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049; PubMed:7622471; PubMed:9553099). Receptor activation stimulates chemotaxis; granule enzyme release; intracellular calcium release and superoxide anion production.
- Versandbedingungen:
- Ambient