Human ANGPT2 Protein; hFc Tag

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£171.00

SKU:: PME100823
Zusätzliche Namen:: ANGPT2;GPT2;NG2;ngiopoietin-2
Molekulargewicht:: The protein has a predicted molecular mass of 49.94 kDa after removal of the signal peptide.
Reinheit:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ANGPT2
ANGPT2(Lys275-Phe496) hFc(Glu99-Ala330):: ANGPT2(Lys275-Phe496) hFc(Glu99-Ala330)
Weitere Details:: The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1); and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.