PME100811
Human CD130 Protein; hFc Tag
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£171.00
- SKU:
- PME100811
- Zusätzliche Namen:
- CD130;CDW130;GP130;IL-6RB
- Molekulargewicht:
- The protein has a predicted molecular mass of 91.19 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CD130
- CD130(Glu23-Glu619) hFc(Glu99-Ala330):
- CD130(Glu23-Glu619) hFc(Glu99-Ala330)
- Weitere Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines; including interleukin 6 (IL6); ciliary neurotrophic factor (CNTF); leukemia inhibitory factor (LIF); and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6; a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus; can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Versandbedingungen:
- Ambient