PME100802
Human CDH3 Protein; His Tag
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£171.00
- SKU:
- PME100802
- Zusätzliche Namen:
- CDHP;HJMD;PCAD
- Molekulargewicht:
- The protein has a predicted molecular mass of 60.9 kDa after removal of the signal peptide. The apparent molecular mass of CDH3-His is approximately 70-100 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CDH3
- CDH3(Asp108-Gly654) 6×His tag:
- CDH3(Asp108-Gly654) 6×His tag
- Weitere Details:
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition; aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia; ectrodactyly; and macular dystrophy syndrome (EEMS). [provided by RefSeq; Nov 2015]
- Versandbedingungen:
- Ambient