PME100799
Human CXCR3 Protein; mFc Tag
Größe
£184.00
- SKU:
- PME100799
- Zusätzliche Namen:
- CXC-R3;CXCR-3;CKR-L2;IP-10 receptor;CD183;GPR9
- Molekulargewicht:
- The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of CXCR3-mFc is approximately 25-55 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CXCR3
- CXCR3(Met1-Arg53) mFc(Pro99-Lys330):
- CXCR3(Met1-Arg53) mFc(Pro99-Lys330)
- Weitere Details:
- This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9/Mig (monokine induced by interferon-g); CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4/PF4 (PMID:12782716). [provided by RefSeq; Jun 2011]
- Versandbedingungen:
- Ambient