PME100727
Human PRNP Protein; hFc Tag
Größe
£177.00
- SKU:
- PME100727
- Zusätzliche Namen:
- PrP;ASCR;PrP27-30;PrP33-35C;CD230
- Molekulargewicht:
- The protein has a predicted molecular mass of 48.8 kDa after removal of the signal peptide. The apparent molecular mass of PRNP-hFc is approximately 55-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- PRNP
- PRNP(Lys23-Gly229) hFc(Glu99-Ala330):
- PRNP(Lys23-Gly229) hFc(Glu99-Ala330)
- Weitere Details:
- The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20; approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease; fatal familial insomnia; Gerstmann-Straussler disease; Huntington disease-like 1; and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller; structurally unrelated protein; AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Nov 2014]
- Versandbedingungen:
- Ambient