PME100598
Human UPA Protein; His Tag
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£171.00
- SKU:
- PME100598
- Zusätzliche Namen:
- ATF;BDPLT5;QPD;u-PA;UPA;URK
- Molekulargewicht:
- The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide. The apparent molecular mass of UPA-His is approximately 55-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- UPA
- UPA(Ser21-Leu431) 6×His tag:
- UPA(Ser21-Leu431) 6×His tag
- Weitere Details:
- This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq; Jan 2016]
- Versandbedingungen:
- Ambient