Human PD-1 Protein; His tag

Größe

£171.00

SKU:: PME100461
Zusätzliche Namen:: PDCD1;PD1;CD279;SLEB2
Molekulargewicht:: The protein has a predicted molecular mass of 16.8 kDa after removal of the signal peptide.
Reinheit:: The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: PD-1
PD-1(Leu25-Gln167) 6×His tag:: PD-1(Leu25-Gln167) 6×His tag
Weitere Details:: This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice; expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.