PME100377
Human P2RX7 Protein; hFc Tag
Größe
£181.00
- SKU:
- PME100377
- Zusätzliche Namen:
- P2X7
- Molekulargewicht:
- The protein has a predicted molecular mass of 59.2 kDa after removal of the signal peptide. The apparent molecular mass of hFc-P2RX7 is approximately 55-70 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- P2RX7
- hFc(Glu99-Ala330) P2RX7(Ser47-Val334):
- hFc(Glu99-Ala330) P2RX7(Ser47-Val334)
- Weitere Details:
- The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified; most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq; Jul 2010]
- Versandbedingungen:
- Ambient