PME100301
Human IL21R Protein; hFc Tag
Größe
£184.00
- SKU:
- PME100301
- Zusätzliche Namen:
- CD360;IMD56;NILR
- Molekulargewicht:
- The protein has a predicted molecular mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of IL21R-hFc is approximately 55-100 kDa due to glycosylation.
- Reinheit:
- The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- IL21R
- IL21R(Cys20-Glu232) hFc(Glu99-Ala330):
- IL21R(Cys20-Glu232) hFc(Glu99-Ala330)
- Weitere Details:
- The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors; and has been shown to form a heterodimeric receptor complex with the common gamma-chain; a receptor subunit also shared by the receptors for interleukin 2; 4; 7; 9; and 15. This receptor transduces the growth promoting signal of IL21; and is important for the proliferation and differentiation of T cells; B cells; and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules; including JAK1; JAK3; STAT1; and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
- Versandbedingungen:
- Ambient