Human PVRIG Protein; hFc Tag

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£177.00

SKU:: PME100090
Zusätzliche Namen:: C7orf15;CD112R
Molekulargewicht:: The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation.
Reinheit:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Formulierung:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: PVRIG
PVRIG(Met1-Thr25 Pro80-Ala170) hFc(Glu99-Ala330):: PVRIG(Met1-Thr25 Pro80-Ala170) hFc(Glu99-Ala330)
Weitere Details:: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2; inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]