PME100076
Human TNFa Protein; His Tag
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£190.00
- SKU:
- PME100076
- Zusätzliche Namen:
- DIF;TNF-alpha;TNFA;TNFSF2;cachexin;cachectin;TNFα
- Molekulargewicht:
- The protein has a predicted molecular mass of 18.1 kDa after removal of the signal peptide.
- Reinheit:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- TNFA
- TNFα(Arg78-Leu233) 6×His tag:
- TNFα(Arg78-Leu233) 6×His tag
- Weitere Details:
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to; and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation; differentiation; apoptosis; lipid metabolism; and coagulation. This cytokine has been implicated in a variety of diseases; including autoimmune diseases; insulin resistance; and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
- Versandbedingungen:
- Ambient