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PME-M100069

Mouse ROR1 Protein; His Tag

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£202.00

SKU:
PME-M100069
Zusätzliche Namen:
Ror1
Molekulargewicht:
The protein has a predicted molecular mass of 42.6 kDa after removal of the signal peptide. The apparent molecular mass of mROR1-His is approximately 55-70 kDa due to glycosylation.
Reinheit:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
DIMA Biotechnology Ltd
Formulierung:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
ROR1
Mouse ROR1(Gln30-Glu403) 6×His tag:
Mouse ROR1(Gln30-Glu403) 6×His tag
Weitere Details:
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq; Jun 2012]
Versandbedingungen:
Ambient