Anti-IGFBP7 antibody(DMC422); IgG1 Chimeric mAb

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£198.00

SKU:: DMC100422
Zusätzliche Namen:: IBP-7; TAF; IGFBP-rP1; MAC25 protein
Anwendung:: Flow Cytometry
Aufreinigung:: Purified from cell culture supernatant by affinity chromatography
Lagerbedingungen:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:: DIMA Biotechnology Ltd
Host:: Rabbit
Reaktivitäten:: Human
Formulierung:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Klon:: DMC422
Target:: IGFBP7
Weitere Details:: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).