DMC100283
Anti-CD162 antibody(DMC283); IgG1 Chimeric mAb
Größe
£198.00
- SKU:
- DMC100283
- Zusätzliche Namen:
- PSGL-1;PSGL1;CD162;SELPLG;Selectin P ligand
- Anwendung:
- Flow Cytometry
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- DIMA Biotechnology Ltd
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Formulierung:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Klon:
- DMC283
- Target:
- SELPLG
- Weitere Details:
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Ambient