Phospholamban Adenovirus (Ad-Phospholamban)

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£882.00

SKU:: 1570
Zusätzliche Namen:: Ad-Phospholamban|Phospholamban Adenovirus
Konzentration:: 1E10 PFU/ml
Lagerbedingungen:: -70[o]C Avoid freeze/thaw cycles.
Hersteller:: Vector Biolabs
Buffer:: DMEM, 2% BSA, 2.5% Glycerol
Spezies:: Virus
Weitere Details:: Phospholamban (PLB, sarco(endo)plasmic-reticulum (SER) regulatory protein) is a 52 amino acid phospho-protein that assembles into a pentamer in the plasma membrane of SER cardiac, smooth and slow-twitch muscle. PLB may regulate cardiac contractility through modulation of SER Ca2+ ATPase (SERCA2a). Nonphosphorylated PLB binds to SERCA2a and inhibits Ca2+ re-uptake into the SER. Phosphorylation of PLB causes dissociation from SERCA2a, allowing Ca2+ uptake into the SER and subsequent ventricular relaxation., vectorbiolabs