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1557

Dual specificity phosphatase 6 Adenovirus (Ad-MKP3)

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£882.00

SKU:
1557
Zusätzliche Namen:
Ad-MKP3|Dual specificity phosphatase 6 Adenovirus
Konzentration:
1E10 PFU/ml
Lagerbedingungen:
-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Vector Biolabs
Buffer:
DMEM, 2% BSA, 2.5% Glycerol
Spezies:
Virus
Weitere Details:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm., vectorbiolabs
Versandbedingungen:
Dry Ice