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1405

Protein phosphatase 1A (formerly 2C), alpha isoform Adenovirus (Ad-PP1A)

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£882.00

SKU:
1405
Zusätzliche Namen:
Ad-PP1A|Protein phosphatase 1A (formerly 2C), alpha isoform Adenovirus
Konzentration:
1E10 PFU/ml
Lagerbedingungen:
-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Vector Biolabs
Buffer:
DMEM, 2% BSA, 2.5% Glycerol
Spezies:
Virus
Weitere Details:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis., vectorbiolabs
Versandbedingungen:
Dry Ice