1142
TLR2 Adenovirus (Ad-CMV-TLR2)
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£631.00
- SKU:
- 1142
- Zusätzliche Namen:
- Ad-CMV-TLR2|TLR2 Adenovirus
- Konzentration:
- 1E10 PFU/ml
- Lagerbedingungen:
- -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Vector Biolabs
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Spezies:
- Virus
- Weitere Details:
- Toll-like Receptor 2 Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated tolllike receptors (TLR). Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo and also participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFIB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes., vectorbiolabs
- Versandbedingungen:
- Dry Ice