Nod2 (CARD15) Adenovirus (Ad-CMV-Nod2)

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£631.00

SKU:: 1141
Zusätzliche Namen:: Ad-CMV-Nod2|Nod2 (CARD15) Adenovirus
Konzentration:: 1E10 PFU/ml
Lagerbedingungen:: -70[o]C Avoid freeze/thaw cycles.
Hersteller:: Vector Biolabs
Buffer:: DMEM, 2% BSA, 2.5% Glycerol
Spezies:: Virus
Weitere Details:: Nucleotide-binding oligomerization domain protein 2 The mammalian homologs of the Ced-4 proteins, Apaf-1 (Ced-4), Nod1 (CARD4), and Nod2 (CARD15) contain a caspase recruitment domain (CARD) and a putative nucleotide binding domain, signified by a consensus Walker's A box (P-loop) and B box (Mg2+-binding site). Nod2 is composed of two N-terminal CARDs, a nucleotide-binding domain, and multiple C-terminal leucine-rich repeats. The expression of Nod2 is highly restricted to monocytes, and activates NFIB in response to bacterial lipopolysaccharides., vectorbiolabs