Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2)

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£537.00

SKU:: Z0422-01C
Anwendung:: WB
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa50 to 400 of human ZIC2.
Format:: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Weitere Details:: Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects. Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 4-7ug/ml Optimal dilutions to be determined by the researcher. Positive Control: HepG2 call lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.